Series episode
| Tim Roth | ... | Dr. Cal Lightman |
| Kelli Williams | ... | Dr. Gillian Foster |
| Brendan Hines | ... | Eli Loker |
| Monica Raymund | ... | Ria Torres |
| Mekhi Phifer | ... | Agent Ben Reynolds |
| Sean Patrick Thomas | ... | Karl Dupree |
| Molly Price | ... | Deputy Director Messler |
| Jonathan Banks | ... | Bitcher |
| Hayley McFarland | ... | Emily Lightman |
| Anthony Azizi | ... | Omar Kahn |
| Bernard White | ... | Imam Amir Hadad |
| Don Wallace | ... | Sharif Hamza Ali |
| Anne Bedian | ... | Hasina Kahn |
| Jennifer Beals | ... | Zoe Landau |
| Karim Saleh | ... | Nabil Kahn |
| Walid Amini | ... | Walid |
| Oren Dayan | ... | Jamal Bata |
| Nick McDow | ... | Rasheed |
| Gary Kraus | ... | Bus Driver |
| Monyque Thompson Scott | ... | Nurse |
| Victoria Recaño | ... | Reporter |
| Basilina Butler | ... | Bus Bomb Survivor |
| Matthew Del Negro | ... | Agent Young |
| Chad Olshavsky | ... | Frantic Family Member |
| Erin Pickett | ... | Bus Passenger |
| Cindy Saavedra | ... | Nurse |
| Richard Schimmelpfenneg | ... | Fireman |
| Adam Davidson | ... | Direction |
| Josh Singer Dustin Thomason | ... | Script |