Series episode
Cast: (19 - show/hide all)
| Jonny Lee Miller | ... | Sherlock Holmes |
| Lucy Liu | ... | Dr. Joan Watson |
| Catherine Blades | ... | Olivia |
| Madaí Chakell | ... | Chivonne |
| Delia Cunningham | ... | Dana |
| Nelsan Ellis | ... | Shinwell Johnson |
| Alisa Ermolaev | ... | Anezka |
| Jon Michael Hill | ... | Detective Marcus Bell |
| Brian Hutchison | ... | Kurt Godwyn |
| Connor Johnston | ... | Tendu |
| James Kyson | ... | Joey Ng |
| Andrew Manning | ... | Lucien |
| Kelly McAndrew | ... | Washington |
| Bobby Moreno | ... | O.G. Pwnzr |
| Kathy Najimy | ... | Rayna Carno |
| Aidan Quinn | ... | Captain Thomas Gregson |
| Olesya Senchenko | ... | Libena |
| Christine Taylor | ... | Ms. Linquest |
| Rachel York | ... | Carla Giovanni |
Crew:
| John Polson | ... | Direction |
| Robert Hewitt Wolfe | ... | Script |