| Rory Cochrane | ... | Tim Speedle (50 episodes) |
| Christian Clemenson | ... | Dr. Tom Loman (45 episodes) |
| David Lee Smith | ... | IAB Sergeant Rick Stetler (34 episodes) |
| Brendan Fehr | ... | Dan Cooper (34 episodes) |
| Brian Poth | ... | Tyler Jenson (29 episodes) |
| Christopher Redman | ... | Michael Travers (25 episodes) |
| Eddie Cibrian | ... | Jesse Cardoza (25 episodes) |
| Megalyn Echikunwoke | ... | Dr. Tara Price (23 episodes) |
| Wes Ramsey | ... | Kip Miller (21 episodes) |
| Evan Ellingson | ... | Kyle Harmon (17 episodes) |
| Brooke Bloom | ... | Cynthia Wells (16 episodes) |
| Armando Valdes-Kennedy | ... | Aaron Peters (15 episodes) |
| Shelli Bergh | ... | Paula Muro (12 episodes) |
| Alana De La Garza | ... | Marisol Delko (12 episodes) |
| Johnny Whitworth | ... | Detective Jake Berkeley (12 episodes) |
| Holt McCallany | ... | Detective John Hagen (11 episodes) |
| Kim Delaney | ... | Megan Donner (10 episodes) |
| Wanda De Jesus | ... | Detective Adell Sevilla (10 episodes) |
| Christina Chang | ... | State Attorney Rebecca Nevins (10 episodes) |
| Leslie Odom Jr. | ... | Joseph Kayle (9 episodes) |
| Joel West | ... | Officer Ramirez (9 episodes) |
| Amy Laughlin | ... | Erica Sikes (9 episodes) |
| Elizabeth Berkley | ... | Julia Winston (9 episodes) |
| Michael Whaley | ... | Detective Bernstein (7 episodes) |
| Michael B. Silver | ... | FBI Agent Peter Elliott (7 episodes) |
| Raniel David Castillo | ... | Police Officer (7 episodes) |
| Chris Krauser | ... | Lifeguard (7 episodes) |
| Bellamy Young | ... | Assistant State Attorney Monica West (6 episodes) |
| Kim Coates | ... | Ron Saris (6 episodes) |
| Salli Richardson-Whitfield | ... | Laura (5 episodes) |
| Stephen Tobolowsky | ... | Assistant State Attorney Don Haffman (5 episodes) |
| Cristián de la Fuente | ... | Sam Belmontes (5 episodes) |
| Taylor Cole | ... | Taylor (5 episodes) |
| Robert LaSardo | ... | Memmo Fierro (5 episodes) |
| Ed Begley Jr. | ... | Scott O'Shay (5 episodes) |
| Mohammad Kavianpour | ... | Co-Pilot (5 episodes) |
| John Heard | ... | Kenwall 'Duke' Duquesne (4 episodes) |
| Azura Skye | ... | Susie Barnam (4 episodes) |
| Gonzalo Menendez | ... | Clavo Cruz (4 episodes) |
| Lesley Fera | ... | Dr. Joyce Carmel (4 episodes) |
